<?xml version="1.0" encoding="UTF-8"?><xml><records><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Estes, M. L.</style></author><author><style face="normal" font="default" size="100%">McAllister, A. K.</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Maternal immune activation: Implications for neuropsychiatric disorders</style></title><secondary-title><style face="normal" font="default" size="100%">Science</style></secondary-title><alt-title><style face="normal" font="default" size="100%">Science (New York, N.Y.)</style></alt-title><short-title><style face="normal" font="default" size="100%">Science (New York, N.Y.)Science (New York, N.Y.)</style></short-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Adolescent</style></keyword><keyword><style  face="normal" font="default" size="100%">Animals</style></keyword><keyword><style  face="normal" font="default" size="100%">Autism Spectrum Disorder/epidemiology/*immunology</style></keyword><keyword><style  face="normal" font="default" size="100%">Brain/*immunology/physiopathology</style></keyword><keyword><style  face="normal" font="default" size="100%">Child</style></keyword><keyword><style  face="normal" font="default" size="100%">Child, Preschool</style></keyword><keyword><style  face="normal" font="default" size="100%">Disease Models, Animal</style></keyword><keyword><style  face="normal" font="default" size="100%">Female</style></keyword><keyword><style  face="normal" font="default" size="100%">Gastrointestinal Tract/immunology</style></keyword><keyword><style  face="normal" font="default" size="100%">Humans</style></keyword><keyword><style  face="normal" font="default" size="100%">Immune System Diseases/epidemiology/*immunology</style></keyword><keyword><style  face="normal" font="default" size="100%">Immune System/immunology</style></keyword><keyword><style  face="normal" font="default" size="100%">Mothers</style></keyword><keyword><style  face="normal" font="default" size="100%">Pregnancy</style></keyword><keyword><style  face="normal" font="default" size="100%">Pregnancy Complications, Infectious/epidemiology/*immunology</style></keyword><keyword><style  face="normal" font="default" size="100%">Risk Factors</style></keyword><keyword><style  face="normal" font="default" size="100%">Schizophrenia/epidemiology/*immunology</style></keyword><keyword><style  face="normal" font="default" size="100%">Young Adult</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2016</style></year><pub-dates><date><style  face="normal" font="default" size="100%">Aug 19</style></date></pub-dates></dates><number><style face="normal" font="default" size="100%">6301</style></number><edition><style face="normal" font="default" size="100%">2016/08/20</style></edition><volume><style face="normal" font="default" size="100%">353</style></volume><pages><style face="normal" font="default" size="100%">772-7</style></pages><isbn><style face="normal" font="default" size="100%">0036-8075</style></isbn><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">Epidemiological evidence implicates maternal infection as a risk factor for autism spectrum disorder and schizophrenia. Animal models corroborate this link and demonstrate that maternal immune activation (MIA) alone is sufficient to impart lifelong neuropathology and altered behaviors in offspring. This Review describes common principles revealed by these models, highlighting recent findings that strengthen their relevance for schizophrenia and autism and are starting to reveal the molecular mechanisms underlying the effects of MIA on offspring. The role of MIA as a primer for a much wider range of psychiatric and neurologic disorders is also discussed. Finally, the need for more research in this nascent field and the implications for identifying and developing new treatments for individuals at heightened risk for neuroimmune disorders are considered.</style></abstract><accession-num><style face="normal" font="default" size="100%">27540164</style></accession-num><notes><style face="normal" font="default" size="100%">1095-9203&lt;br/&gt;Estes, Myka L&lt;br/&gt;McAllister, A Kimberley&lt;br/&gt;P50 MH106438/MH/NIMH NIH HHS/United States&lt;br/&gt;R01 NS060125/NS/NINDS NIH HHS/United States&lt;br/&gt;P50-MH106438-01/MH/NIMH NIH HHS/United States&lt;br/&gt;R01-NS060125-05/NS/NINDS NIH HHS/United States&lt;br/&gt;Journal Article&lt;br/&gt;Research Support, N.I.H., Extramural&lt;br/&gt;Research Support, Non-U.S. Gov't&lt;br/&gt;Review&lt;br/&gt;United States&lt;br/&gt;Science. 2016 Aug 19;353(6301):772-7. doi: 10.1126/science.aag3194.</style></notes><custom2><style face="normal" font="default" size="100%">PMC5650490</style></custom2><custom6><style face="normal" font="default" size="100%">NIHMS911626</style></custom6><auth-address><style face="normal" font="default" size="100%">Center for Neuroscience, University of California Davis, One Shields Avenue, Davis, CA 95618, USA.&lt;br/&gt;Center for Neuroscience, University of California Davis, One Shields Avenue, Davis, CA 95618, USA. kmcallister@ucdavis.edu.</style></auth-address><remote-database-provider><style face="normal" font="default" size="100%">NLM</style></remote-database-provider></record></records></xml>