<?xml version="1.0" encoding="UTF-8"?><xml><records><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Kim, P.</style></author><author><style face="normal" font="default" size="100%">Leckman, J. F.</style></author><author><style face="normal" font="default" size="100%">Mayes, L. C.</style></author><author><style face="normal" font="default" size="100%">Feldman, R.</style></author><author><style face="normal" font="default" size="100%">Wang, X.</style></author><author><style face="normal" font="default" size="100%">Swain, J. E.</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">The plasticity of human maternal brain: longitudinal changes in brain anatomy during the early postpartum period</style></title><secondary-title><style face="normal" font="default" size="100%">Behav Neurosci</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Adult</style></keyword><keyword><style  face="normal" font="default" size="100%">Brain/*anatomy &amp; histology</style></keyword><keyword><style  face="normal" font="default" size="100%">Female</style></keyword><keyword><style  face="normal" font="default" size="100%">Humans</style></keyword><keyword><style  face="normal" font="default" size="100%">Magnetic Resonance Imaging</style></keyword><keyword><style  face="normal" font="default" size="100%">Maternal Behavior/*psychology</style></keyword><keyword><style  face="normal" font="default" size="100%">Nerve Fibers, Unmyelinated</style></keyword><keyword><style  face="normal" font="default" size="100%">Neuronal Plasticity</style></keyword><keyword><style  face="normal" font="default" size="100%">Postpartum Period/*psychology</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2010</style></year><pub-dates><date><style  face="normal" font="default" size="100%">Oct</style></date></pub-dates></dates><number><style face="normal" font="default" size="100%">5</style></number><volume><style face="normal" font="default" size="100%">124</style></volume><pages><style face="normal" font="default" size="100%">695-700</style></pages><isbn><style face="normal" font="default" size="100%">1939-0084 (Electronic)&lt;br/&gt;0735-7044 (Linking)</style></isbn><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">Animal studies suggest that structural changes occur in the maternal brain during the early postpartum period in regions such as the hypothalamus, amygdala, parietal lobe, and prefrontal cortex and such changes are related to the expression of maternal behaviors. In an attempt to explore this in humans, we conducted a prospective longitudinal study to examine gray matter changes using voxel-based morphometry on high resolution magnetic resonance images of mothers' brains at two time points: 2-4 weeks postpartum and 3-4 months postpartum. Comparing gray matter volumes across these two time points, we found increases in gray matter volume of the prefrontal cortex, parietal lobes, and midbrain areas. Increased gray matter volume in the midbrain including the hypothalamus, substantia nigra, and amygdala was associated with maternal positive perception of her baby. These results suggest that the first months of motherhood in humans are accompanied by structural changes in brain regions implicated in maternal motivation and behaviors.</style></abstract><accession-num><style face="normal" font="default" size="100%">20939669</style></accession-num><notes><style face="normal" font="default" size="100%">Kim, Pilyoung&lt;br/&gt;Leckman, James F&lt;br/&gt;Mayes, Linda C&lt;br/&gt;Feldman, Ruth&lt;br/&gt;Wang, Xin&lt;br/&gt;Swain, James E&lt;br/&gt;eng&lt;br/&gt;K05MH076273/MH/NIMH NIH HHS/&lt;br/&gt;RC2 MD004767/MD/NIMHD NIH HHS/&lt;br/&gt;5K05DA020091/DA/NIDA NIH HHS/&lt;br/&gt;K05 DA020091/DA/NIDA NIH HHS/&lt;br/&gt;T32 MH018268/MH/NIMH NIH HHS/&lt;br/&gt;K05 MH076273/MH/NIMH NIH HHS/&lt;br/&gt;Research Support, N.I.H., Extramural&lt;br/&gt;Research Support, Non-U.S. Gov't&lt;br/&gt;Research Support, U.S. Gov't, Non-P.H.S.&lt;br/&gt;2010/10/14 06:00&lt;br/&gt;Behav Neurosci. 2010 Oct;124(5):695-700. doi: 10.1037/a0020884.</style></notes><custom2><style face="normal" font="default" size="100%">4318549</style></custom2><auth-address><style face="normal" font="default" size="100%">Department of Human Development, Cornell University. pilyoung.kim@nih.gov</style></auth-address></record></records></xml>