@article {321,
	title = {Role of genotype in the cycle of violence in maltreated children.},
	journal = {Science},
	volume = {297},
	year = {2002},
	month = {2002 Aug 2},
	pages = {851-4},
	abstract = {<p>We studied a large sample of male children from birth to adulthood to determine why some children who are maltreated grow up to develop antisocial behavior, whereas others do not. A functional polymorphism in the gene encoding the neurotransmitter-metabolizing enzyme monoamine oxidase A (MAOA) was found to moderate the effect of maltreatment. Maltreated children with a genotype conferring high levels of MAOA expression were less likely to develop antisocial problems. These findings may partly explain why not all victims of maltreatment grow up to victimize others, and they provide epidemiological evidence that genotypes can moderate children\&$\#$39;s sensitivity to environmental insults.</p>
},
	keywords = {Adolescent, Adult, Antisocial Personality Disorder, Chi-Square Distribution, Child, Child Abuse, Child, Preschool, Environment, Genetics, Behavioral, Genotype, Humans, Longitudinal Studies, Male, Minisatellite Repeats, Monoamine Oxidase, Polymorphism, Genetic, Promoter Regions, Genetic, Violence},
	issn = {1095-9203},
	doi = {10.1126/science.1072290},
	author = {Caspi, Avshalom and McClay, Joseph and Moffitt, Terrie E and Mill, Jonathan and Martin, Judy and Craig, Ian W and Taylor, Alan and Poulton, Richie}
}
