@article {2786, title = {Demographic, maltreatment, and neurobiological correlates of PTSD symptoms in children and adolescents}, journal = {J Pediatr Psychol}, volume = {35}, number = {5}, year = {2010}, note = {De Bellis, Michael D
Hooper, Stephen R
Woolley, Donald P
Shenk, Chad E
eng
K24 DA028773/DA/NIDA NIH HHS/
K24 MH071434/MH/NIMH NIH HHS/
K24 MH071434-01A1/MH/NIMH NIH HHS/
K24 MH071434-02/MH/NIMH NIH HHS/
K24 MH071434-03/MH/NIMH NIH HHS/
K24 MH071434-04/MH/NIMH NIH HHS/
K24 MH071434-05/MH/NIMH NIH HHS/
K24MH071434/MH/NIMH NIH HHS/
R01 AA012479/AA/NIAAA NIH HHS/
R01 MH061744/MH/NIMH NIH HHS/
R01 MH063407/MH/NIMH NIH HHS/
R01-75 MH61744/MH/NIMH NIH HHS/
R01-AA12479/AA/NIAAA NIH HHS/
R01-MH63407/MH/NIMH NIH HHS/
T32 DK063929/DK/NIDDK NIH HHS/
Research Support, N.I.H., Extramural
2009/12/17 06:00
J Pediatr Psychol. 2010 Jun;35(5):570-7. doi: 10.1093/jpepsy/jsp116. Epub 2009 Dec 11.}, month = {Jun}, pages = {570-7}, abstract = {OBJECTIVE: To examine the relationships of demographic, maltreatment, neurostructural and neuropsychological measures with total posttraumatic stress disorder (PTSD) symptoms. METHODS: Participants included 216 children with maltreatment histories (N = 49), maltreatment and PTSD (N = 49), or no maltreatment (N = 118). Participants received diagnostic interviews, brain imaging, and neuropsychological evaluations. RESULTS: We examined a hierarchical regression model comprised of independent variables including demographics, trauma and maltreatment-related variables, and hippocampal volumes and neuropsychological measures to model PTSD symptoms. Important independent contributors to this model were SES, and General Maltreatment and Sexual Abuse Factors. Although hippocampal volumes were not significant, Visual Memory was a significant contributor to this model. CONCLUSIONS: Similar to adult PTSD, pediatric PTSD symptoms are associated with lower Visual Memory performance. It is an important correlate of PTSD beyond established predictors of PTSD symptoms. These results support models of developmental traumatology and suggest that treatments which enhance visual memory may decrease symptoms of PTSD.}, keywords = {*Image Processing, Computer-Assisted, *Magnetic Resonance Imaging, Adolescent, Child, Child Abuse, Sexual/*psychology/*statistics \& numerical data, Child Abuse/*psychology/*statistics \& numerical data, Child, Preschool, Dominance, Cerebral/physiology, Female, Hippocampus/*pathology, Humans, Interview, Psychological, Male, Memory, Short-Term/physiology, Neuropsychological Tests/*statistics \& numerical data, North Carolina, Organ Size/physiology, Pattern Recognition, Visual/physiology, Post-Traumatic/diagnosis/epidemiology/*physiopathology/*psychology, Psychometrics, Socioeconomic Factors, Stress Disorders,}, isbn = {1465-735X (Electronic)
0146-8693 (Linking)}, doi = {https://doi.org/10.1093/jpepsy/jsp116}, author = {De Bellis, M. D. and Hooper, S. R. and Woolley, D. P. and Shenk, C. E.} }