@article {250,
	title = {Effects of an attachment-based intervention on daily cortisol moderated by dopamine receptor D4: a randomized control trial on 1- to 3-year-olds screened for externalizing behavior.},
	journal = {Dev Psychopathol},
	volume = {20},
	year = {2008},
	month = {2008 Summer},
	pages = {805-20},
	abstract = {<p>The effect of the Video-Feedback Intervention to Promote Positive Parenting and Sensitive Discipline (VIPP-SD) on daily cortisol production was tested in a randomized controlled trial with 130 families with 1- to 3-year-old children screened for their relatively high levels of externalizing behavior. Six 1.5-hr intervention sessions focusing on maternal sensitivity and discipline were conducted with individual families at their homes. Children in the intervention group showed lower cortisol levels, with a moderating role of the dopamine receptor D4 (DRD4) VNTR exon III polymorphism. The VIPP-SD program proved to be effective in decreasing daily cortisol production in children with the DRD4 7-repeat allele, but not in children without the DRD4 7-repeat allele. Our findings indicate that children are differentially susceptible to intervention effects dependent on the presence of the 7-repeat DRD4 allele.</p>
},
	keywords = {Alleles, Arousal, Behavior Therapy, Child Behavior Disorders, Child, Preschool, Education, Exons, Genetic Predisposition to Disease, Humans, Hydrocortisone, Infant, Internal-External Control, Minisatellite Repeats, Mother-Child Relations, Object Attachment, Polymorphism, Genetic, Receptors, Dopamine D4, Temperament, Video Recording},
	issn = {1469-2198},
	doi = {10.1017/S0954579408000382},
	author = {Bakermans-Kranenburg, Marian J and Van IJzendoorn, Marinus H and Mesman, Judi and Alink, Lenneke R A and Juffer, Femmie}
}
